Examples are distearoylphosphatidyl-ethanolamine (DSPE)-PEG conjugates altered with disulphide linkers (e.g., DSPE-SS-PEG), which provide responsiveness in tumour cells exhibiting heightened redox potential [90]
The clinical efficacy of glutathione is also supported by large-scale patient-reported outcomes among people managing the overlapping triad of Long COVID, ME/CFS, and POTS/dysautonomia, where glutathione therapies are frequently rated among the more helpful interventions for this complex neuroimmune symptom cluster
Toxicology 2019;422:1424
Bennett BJ, Vallim TQ, Wang Z, Shih DM, Meng Y, Gregory J, Allayee H, Lee R, Graham M, Crooke R, Edwards PA, Hazen SL, Lusis AJ: Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation
It is used to treat symptoms of chronic ailments such as Fibromylagia, chronic fatigue, migraines, muscle spasms and vitamin deficencies