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Introduction ~2.1% of the US population aged 9 years of age) Cons : anticholinergic side effects such as dry eyes, dry mouth, blurred vision (need to emphasize the need to wash hands thoroughly after use to minimize risk), long-term therapy, may be costly Systemic anticholinergics: off-label use for hyperhidrosis Glycopyrrolate Can start at 1mg twice daily and increase up to 6mg a day, or until limited by anticholinergic side effects Oxybutynin Can start at 5 to 10mg daily and increase to 15 to 20mg daily A study in kids showed a 90% response rate at 2mg daily

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