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Furthermore, research finds HSF1 not only induces heat shock protein expression to maintain proteostasis but also directly interacts with the NLRP3 inflammasome under stress conditions, thereby suppressing its aberrant activation [58, 59]

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The oxidant stress that results from impaired homocysteine metabolism, which modifies the intracellular redox status, might play a central role in the molecular mechanisms underlying moderate hyperhomocysteinemia-mediated vascular disorders

Materials and methods Experimental animals In the current study, 60 adult male spargue-dawley rats (10 weeks old) weighting 250 20 g were purchased from the animal laboratory center of Shiraz University of Medical Sciences to evaluate the effect of MSG and L-Ca

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