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In Leydig cell models, LHCGR activation raises cAMP, promoting StAR-mediated transfer of cholesterol into mitochondria

Ratt S, Hong S, De Schutter E, Prescott SA

Exposure at the highest concentrations (100 and 200 ppm) significantly reduced hatching rate and survival, probably owing to the aggregation of PET NPs on the chorion surface, which could block the pores and prevent the exchange of oxygen and nutrients and possibly hinder the release of hatching enzymes

Similarly, miR-133a directly regulates the GSTP1 gene in bladder cancer (BC) and mediates GSTP1-mediated anti-apoptotic effects by downregulation of miR-133a in human BC (73)

p53 and zinc: a malleable relationship