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Grunwell, Division of Pediatric Critical Care Medicine, Department of Pediatrics, Childrens Healthcare of Atlanta at Egleston, Emory University School of Medicine, 1405 Clifton Rd

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Modulating parameters such as size, shape, surface charge, stiffness, and surface chemical composition can alter interactions with immune cells, including T cells, dendritic cells (DCs), and macrophages, expanding their applicability for immunological regulation [27]