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When applied topically you can target the affected area for anti-inflammatory effects and systemic absorption

LPS is a major component of the cell wall of Gram-negative bacteria and is the most well-characterized and understood endotoxin that triggers chronic inflammation and neurodegeneration (Qin et al., 2007), which is found in high concentrations in the blood, gut, skin, and gums during bacterial infections

Fox EP, Cowley ES, Nobile CJ, Hartooni N, Newman DK, Johnson AD