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Despite current limitations in counteracting cancer cachexia due to its complex pathogenesis and lack of targeted agents, BPC157, a pentadecapeptide, shows promising potential as a fundamental agent targeting the signaling processes implicated in cancer cachexia

Vitamin A depletion induced by cigarette smoke is associated with an increase in lung cancer-related markers in rats

Analytical methods Cell growth was monitored by measuring OD 600 using a spectrophotometer (OPTIZEN POP, Mecasys, Republic of Korea)

Phagocyte dysfunction and metabolic reprogramming Phagocyte reprogramming in wound infection refers to the dynamic alteration of innate immune cell phenotypes in response to the evolving microenvironment of an infected wound

Hand or face fluid retention Self-reported community timelines describe mild fluid retention particularly noticeable in the hands and around the face during the first 2-4 weeks at higher doses