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Health care professionals should be aware that FDA found no increased risk of SI/B with the use of GLP-1 RA medications and is requesting the removal of this Warning and Precaution from the prescribing information for the GLP-1 RA medications (Saxenda, Wegovy, and Zepbound) that include such language

This result indicates that chronic treatment with GLP-1R agonists could lead to proliferation/chronic activation of PSCs, with serious side effects

Most patients benefit from GLP-1 medications like semaglutide or tirzepatide, but we choose based on your medical profile, insurance coverage, and treatment goals

The study's findings revealed a marked increase in GLP-1RA use among Americans, both with and without a reported history of diabetes, largely driven by increased semaglutide use following its approval for weight management

Molecular and metabolic profiling of cancer biopsies is a novel opportunity to identify new features of solid tumors