Mller PC, Kapp JR, Vetter D, Bonavina L, Brown W, Castro S, Cheong E, Darling GE, Egberts J, Ferri L, Gisbertz SS, Gockel I, Grimminger PP, Hofstetter WL , Hlscher AH, Low DE, Luyer M, Markar SR, Mnig SP, Moorthy K, Morse CR, Mller-Stich BP, Nafteux P, Nieponice A, Nieuwenhuijzen GAP, Nilsson M, Palanivelu C, Pattyn P, Pera M, Rsnen J, Ribeiro U, Rosman C, Schrder W, Sgromo B, van Berge Henegouwen MI, van Hillegersberg R, van Veer H, van Workum F, Watson DI, Wijnhoven BPL, Gutschow CA
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For instance, PPR significantly alters the pharmacokinetics of carbamazepine, increasing its maximum plasma concentration, half-life, and area under the curve by 68.7, 47.9, and 43.2%, respectivelyelevating risks of drug toxicity (85)
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Proc Chemother Foundation Symp, 1998