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The robust triglyceride reduction seen at higher retatrutide doses is attributed to the glucagon receptor pathways direct stimulation of hepatic fat oxidation, which reduces hepatic VLDL secretion and subsequently lowers circulating triglyceride concentrations

or intragastrically i.g., respectively) prior to carbon tetrachloride (CCl 4 ) intoxication showed a significant drop in bilirubin and aspartate aminotransferase as compared to that of the control group