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Stimulants work by forcing the muscles in your intestines to contract aggressively

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More recently, a study presented at the annual meeting of the American Academy of Orthopaedic Surgeons (AAOS) in March 2026 indicated an increased risk of osteoporosis and osteomalacia (bone softening) after five years of taking GLP-1s

If you experience itching, redness, or mild swelling that stays within one to two inches of the injection site, these are expected local reactions that typically fade within 72 hours