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doi: 10.1161/CIRCULATIONAHA.112.091215 39 GuoZQiWYuYDuSWuJLiuJ

The study did not determine the reason patients were prescribed these medications and the severity of the strokes that patients experienced could not be assessed, which may have affected the outcomes

During this process, ROS act as essential intracellular messengers to activate downstream signaling molecules mediating significant changes in the membrane architecture (i.e., membrane destabilization, permeability and lipid redistribution), which are prerequisite for successful fertilization (79)

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However, assessment of long-term, hard clinical kidney endpoints has been limited by the three- to fivefold higher risk of hyperkalaemia with spironolactone use [66]