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The FDA has issued guidance that compounders should wind down production within a defined transition period after a shortage is resolved, though the exact enforcement approach has been subject to legal challenges

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Again, the antioxidant action of DFO in vivo may be of little importance because the blood levels reached during therapy (20 M) are too low to achieve the desired effect (Figure 11A), resulting in amplified transcription of genes promoting erythropoiesis, glycolysis, and angiogenesis (Woo et al., 2006)

If you store a vial incorrectly or use it past the recommended time, it might not work as well

Thus, research on the effects of KD therapy in PD is still at a preliminary stage