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Youre especially vulnerable if you drink regularly or take high doses

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Thus, purine catabolism appears to be a homeostatic response of mitochondria to oxidant stress and may protect against progressive mitochondrial dysfunction in certain disease states (Kristal et al., 1999)

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Int Immunopharmacol 14(4): 67482 Yang Z, Wang Y, Zhang Y et al (2018) RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis [J]