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The first two groups included 36,082 patients using GLP-1 receptor agonists and 234,028 patients using DPP-4 inhibitors between 2007 and 2020, while the other two groups included 32,336 patients using GLP-1 receptor agonists and 96,212 patients using SGLT-2 inhibitors between 2013 and 2020

Outcome Measures and Follow-Up Primary outcome: The percentage change in body weight from baseline to 12 months after intervention is the primary outcome investigated in this study

Tesamorelin is the only growth hormone releasing hormone (GHRH) analogue ever approved by the FDA for human use