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Historia y desarrollo El inters por 5-Amino-1MQ surgi del reconocimiento del papel de la nicotinamida N-metiltransferasa (NNMT) como enzima sobreexpresada en tejido adiposo de modelos de obesidad y en diversos tumores, donde su actividad se vincula con alteraciones del metabolismo de metilos y del NAD+

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pluvialis were shown to occur during the infection process, suggesting that FOCM could potentially be a target site for the development of fungal-specific inhibitors