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B12 also plays a role in cell replication and helps regulate foetal growth

NNMT is an enzyme that grabs nicotinamide and methylates it, turning it into a waste product called 1-MNA that gets cleared from the body

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Concurrent administration with cysteine or N-acetylcysteine enhances hepatic sulfate production, which could alter acetaminophen metabolism and should be considered when treating patients with chronic pain requiring frequent analgesia