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Nature 2011

P., Ajabiya J., Teli D., Bojarska J., Apostolopoulos V

Notably, acetylcarnitine can act as an acetyl donor [37], supporting the acetylation process of cells through the shuttle mechanism of acetylcarnitine in the absence of conventional acetyl-CoA synthetase enzymes such as ATP-citrate lyase (ACLY) and acyl-CoA synthetase short chain 2 (ACSS2) [38]

Its widespread distribution in the nervous system underscores its importance in modulating a wide range of physiological functions [73]

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