There is also some extent to which weight loss happens in the brain, especially when it comes to GLP-1 agonists and GIP agonists, as mentioned in footnote 1
A new aspect of an old friend: the beneficial effect of metformin on anti-tumor immunity
These include: Neurological symptoms : tingling or numbness in hands and feet (peripheral neuropathy), difficulty walking or balance problems, memory difficulties, or mood changes including depression Haematological signs : persistent fatigue, weakness, pale or jaundiced skin, or shortness of breath Glossitis : a sore, red, smooth tongue Cognitive symptoms : difficulty concentrating, confusion, or "brain fog" Seek urgent medical attention if you experience rapidly worsening neurological symptoms, significant difficulty walking, severe paraesthesia, or marked cognitive decline, as these may require immediate assessment
Let your doctor know that exhaustion is preventing you from doing activities that are important to keeping you healthy
This process can add weeks to timeline, so it helps to start early and work closely with your doctor on the documentation