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Alexandria J Med 54:287293

X.ZhenX.WangS.et al

Some patients report that injecting in the thigh produces less nausea than abdominal injections

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Notably, Through a feedback mechanism, mTORC1 inhibition may momentarily increase mTORC2 signaling, causing temporary metabolic disruptions during the first phase of treatment (224), which can transiently disrupt metabolism and frequently leads to hyperlipidemia, necessitating concomitant lipid-lowering therapy (237239)

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