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Studies show that semaglutide (the active ingredient in Wegovy) is associated with the early worsening of diabetic retinopathy

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Dosage & Administration Start with 3 mg once daily for 30 days, then increase to 7 mg

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Recent investigations have reported that PIK3CA mutations modulate SIRT4 expression through negative regulation of the epigenetic factor EP300, ultimately influencing GPT1 and altering glutamine metabolism in cancer [99]