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J Inherit.Metab Dis 9-10-2010

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The beneficial effect of TZT in T2DM and obesity is related to the direct activation of GIP and GLP-1 receptors with subsequent improvement of insulin sensitivity and reduction of bodyweight

The effect was dose-dependent

Hasta la ltima dcada el control glucmico, de la presin arterial, o de la dislipidemia y el uso de inhibidores del sistema renina-angiotensina (iSRA) han sido las nicas estrategias para reducir el riesgo cardiovascular y renal en esta poblacin