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Treatment induces p53-pS15 nuclear exclusion, triggering the apoptotic cascade specifically in senescent fibroblasts while sparing healthy cells

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(18) The study further revealed that the effects of liraglutide on osteoblast differentiation and mitochondrial function were mediated through the GLP-1 receptor (GLP1R), as blocking GLP1R or AMP-activated protein kinase (AMPK) inhibited these outcomes

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