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GLP-1 is a naturally occurring hormone produced in the gut and brain that regulates appetite, blood sugar, and satisfaction after eating

Originally developed to treat Type 2 diabetes, semaglutide has been shown to aid in weight loss by suppressing appetite, slowing digestion, and promoting a feeling of fullness

Semaglutide is administered as a once-weekly subcutaneous injection (marketed as Ozempic for diabetes and Wegovy for weight management) or as a daily oral tablet (Rybelsus)

In their separate trials, the Wegovy pill averaged about 13.6% over 64 weeks and Foundayo about 11.2% over 72 weeks at the top dose

Obesity care providers start by taking a full weight history with patients, checking for relevant comorbidities and then discussing treatment options