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In addition, PFOS induces autophagy-associated apoptosis through ROS-mediated ERK1/2 activation, which is followed by the blockade of the normal autophagic flux in RTCs 3

The research has demonstrated that microglial activation is associated with changes in the expression of various homeostatic markers, such as P2Y12, particularly in patients with MDD [145]

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This step is important because it builds up fat stores for later use