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26 GLP-1 and effects on bone metabolism Several studies show that the GLP-1R is expressed in some bone cells, including osteoclasts and BMSCs, but appears to be absent in mature osteoblasts, indicating a complex role in bone homeostasis that is incompletely understood

On the basis of this, 10 000 simulations were run based on different true ratios (1.00 to 1.15) and on 48 and 42 individuals in total

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Action of GLP-1 on the pancreas Physiology of GLP-1 as an incretin The primary action of GLP-1 for lowering blood glucose is the stimulation of insulin secretion by potentiating the action of glucose (20, 74, 80, 125)