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How often you need B12 injections depends on how severe your deficiency is and why you have it

A 2021 review in Nature Reviews Molecular Cell Biology describes a gradual drop in tissue and cellular NAD+ across aging in rodents and humans, and links that fall to metabolic disease, cognitive decline, and sarcopenia [1]

Missing a single dose of AOD 9604 is unlikely to cause problems or require any compensatory action