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Exp Ther Med 2:10771081

Immune cells of the CNS are primarily compartmentalized within the meninges, choroid plexus, and parenchyma, each with distinct structures and barriers that regulate molecular exchange and immune accessibility

The medications are generally well-tolerated, though gastrointestinal side effects such as nausea, vomiting, and diarrhoea are common, particularly during dose titration

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12 cups of coffee per day is generally considered okay, but avoid energy drinks, which are a triple threat for GI discomfort (caffeine, sugar, and carbonation)