Helali, I., Ferchichi, S., Maaouia, A., Aouni, M
The inhibition of mitochondrial fusion affects mitochondrial fission, which in turn enables the indirect regulation of mitochondrial autophagy
Its methylation levels are carefully controlled by a ternary writing-erasing-reading regulatory system: writers, also known as methyltransferases, include Wilms tumor 1 associated protein (WTAP), methyltransferase-like 3 (METTL3), and methyltransferase-like 14 (METTL14), which are responsible for installing the m 6 A modification
Under these uncontrolled conditions, the concentrations of ROS exceed the capacity of local antioxidant molecules neutralize them (112, 115, 150), resulting in a buildup of ROS O and H 2 O 2 , and also malondialdehyde, at the site of the ovary and in follicular fluid and peritoneal fluid (103, 105, 106, 108, 111, 112)
"Glutathione reductase from human erythrocytes