This increases cost without clear benefit and eliminates the ability to increase dose if initial response is insufficient
In the randomized placebo-controlled HOME trial of 390 adults with type 2 diabetes (de Jager and colleagues, Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B-12 deficiency, BMJ, 2010), metformin lowered serum B12 by a mean of 19 percent over 4.3 years
Lusage de la voie injectable est rserv au traitement des carences lies une malabsorption digestive de la vitamine B 12 ou au traitement de la carence lie un apport alimentaire insuffisant lorsque le recours la voie orale nest pas possible
That said, the right approach depends on your personal health history, current symptoms, and medical needs
We now offer sublingual oral peptide strips a simple, effective alternative to injections