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A 50 mg dose was associated with a higher occurrence of adverse effects apart from constipation compared to 3 mg, 7 mg, 14 mg, and 25 mg doses

The safety and effectiveness of JARDIANCE have not been established in pediatric patients less than 10 years of age as an adjunct to diet and exercise to improve glycemic control in type 2 diabetes mellitus

For example, penicillin has a unique structure as compared to cephalosporins and a low rate of cross-reactivity with cephalosporins

GI side effects are common: nausea, reduced appetite beyond what's useful, occasional digestive disruption