Citrulline is found in high concentration in the liver and is not a component of any major proteins or enzymes, and therefore not much information is available
Early recognition and management can help decrease the severity of interactions
These effects suggest potential upstream modulation of pathways relevant to POD susceptibility
When travelling, use an insulated medication bag with a cool pack (ensuring the pen does not come into direct contact with ice or frozen gel packs, which could cause freezing)
many of these persist or worsen in adulthood.4,12,10 These medical complications can have detrimental effects on quality of life, physical functioning, and psychosocial function.1,2,4,18,19 Individuals with achondroplasia often require multiple surgeries and procedures to alleviate the conditions many complications.6 Condition overview and medical complications A rare genetic condition that leads to well-characterized skeletal dysplasia and serious muscular, neurological, and cardiorespiratory complications