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7 8 9 10 In these cases chronic oxidative stress can be generated, leaving existing anti-oxidant defenses overwhelmed

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biomarkers for sensitivity and rationale for venetoclax-based combination therapies

At the molecular level, bavachin increases the protein expression of PGC-1, SIRT1, nuclear respiratory factor 1 (Nrf1), and mitochondrial transcription factor A (mtTFA) in DKD mice, restores the damaged mitochondrial morphology, enhances mitochondrial biosynthesis, and reduces the number of abnormal mitochondria (Yan et al., 2025)

It preserved endothelium-dependent vessel relaxation via vascular tissue antioxidant content augmentation [44]