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Methods Study Design and Data Source This retrospective cohort study identified adults with evidence of T2DM and a recorded prescription of dulaglutide or semaglutide using the IQVIA Longitudinal Prescription Data (LRx) for France and Italy between February 1, 2020 and December 31, 2022

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Conclusions CaOx crystals exacerbate renal interstitial injury by promoting M1 macrophage polarization and METs formation through the CREB1/CRTC2exosomal miR-93-3pNIK/NF-B2 signaling pathway

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