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Acute toxicity studies in animals, if extrapolated to humans, implicate a single dose of 10-15 grams necessary to produce significant liver toxicity, although several human case reports have shown toxicity at doses less than 4 grams per day (likely due to having one or more risk factors for sensitivity to toxicity) (Amar 2007)

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G6PD is an enzyme that aids in forming glutathione (GSH) and nicotinamide adenine dinucleotide phosphate (NADPH), which are necessary for the oxidation-reduction balance of the body

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5 Human Vaccines and Immunotherapeutics