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By concurrently modulating metabolic dysfunction and inflammatory signaling, GLP-1RAs could potentially reduce the required doses of biologics or other immunosuppressive therapies, thereby minimizing treatment-related toxicity while improving overall disease control

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Chronos Behavioral Health & Wellness

doi: 10.3390/nu12071915

This upregulation during pathological states suggests a potential adaptive response that might enhance sensitivity to GLP-1 agonist therapy during heart failure

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