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Sensitivity analysis 1 accounted for the SURPASS2 full population (without applying the HbA1c inclusion criterion of SUSTAIN FORTE)

SubMagna technology attempts to address these challenges, but the degree to which it succeeds varies by molecule and individual patient factors

For example, insulin resistance and impaired glucose metabolism have been implicated in both conditions

If the protein structure breaks down, the drug may not be able to do its job

Patients should be counseled to store the medication away from the freezer compartment and to be aware of areas in their refrigerator that may be prone to freezing