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Five registered trials, Phase 3 program (Enith1, Enith2) underway

4 Choline deficiency will lead to an accumulation of liver TAG levels, resulting in elevated lipid levels

Given this, based on the above antioxidant classification and defense categories, we selected antioxidants that are more studied in CIPN and have a more significant role in a systematic review to provide a reference for the future application and continued research of antioxidants in CIPN

ALCAR plays an important role in fat metabolism and in the normal function of energy metabolism in most tissues

We synthesize current mechanistic and clinical observations within a framework of energy flux constriction and substrate proportionality, highlighting metabolic factors that may influence nutritional stability during sustained pharmacological weight reduction