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In a major step forward, the FDA approved the first generic liraglutide for weight loss in August 2025, making these treatments more affordable

Injectables, such as retatrutide, CagriSema (cagrilintide and semaglutide), and MariTide (maridebart cafraglutide), are in more advanced clinical trials

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Nevertheless, preliminary estimates can be derived based on the studies currently available

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