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3.3 Ferroptosis in IE related diseases In addition to -thal, IE also happens to be present in various hematological disorders, including congenital dyserythropoietic anemia, hereditary sideroblastic anemia, and anemia in acquired conditions such myelodysplastic syndrome (MDS) ( X-linked sideroblastic anemia is a disease in which mutations in the erythroid-specific 5-aminolevulinate synthase (ALAS2) gene cause excess iron accumulation and, IE

Their vesicular structure enables encapsulation of both hydrophilic and lipophilic drugs, with enhanced dermal penetration and sustained drug release [136]

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24 DIMSCAN cytotoxicity assay The cytotoxicity of BSO and L-PAM was determined in a fixed-ratio of concentration (BSO: L-PAM