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Despite evidence linking elevated levels of ROS to CKD development and progression, the use of low-molecular-weight antioxidants to remove ROS has not been successful in preventing or slowing disease progression

Vitamin B12 deficiency: Foods low in B12 can indirectly contribute to high homocysteine

Carrying excess fat places a constant oxidative burden on cells, but finding balance in energy intake helps ease that hidden pressure at its source

However, scientific research shows that very high-dose oral B12 (1,000-2,000 mcg) can be effective for some, as about 1% can be absorbed without intrinsic factor

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