tirzepatide semaglutide vs Semaglutide: What's the Difference? Semaglutide vs. Tirzepatide for Weight

2024;8:e304

Patrick Kee, MD, PhD, a cardiologist at Vital Heart & Vein, who was not involved in the study, noted the following about the studys results: The investigators demonstrated that the therapeutic efficacy of semaglutide on the primary cardiovascular composite endpoint indeed emerged early and persisted over the initial three months (hazard ratio [HR] 0.63, 95% confidence interval [CI] 0.41-0.95) and the subsequent six months (HR 0.60, 95% CI 0.44-0.81). While the underlying mechanisms of semaglutides early clinical benefits remain under investigation, these findings suggest an encouraging intervention capable of altering the trajectory of [patients with obesity] with established cardiovascular disease but without a diagnosis of diabetes, he told Medical News Today

1 The results were clear: Semaglutide group: 15.8% average weight loss Liraglutide group: 6.4% average weight loss 70.9% of semaglutide participants lost at least 10% of body weight, compared with 25.6% on liraglutide 55.0% of semaglutide participants lost at least 15%, compared with 12.0% on liraglutide This trial provides the strongest available evidence that Wegovy is substantially more effective than Saxenda for weight loss

Los agonistas del receptor GLP-1 son una clase de medicamentos que imitan la accin de la hormona intestinal natural glucagon-like peptide-1

2c , Supplementary Fig