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These findings indicate that the LRRK2PINK1 kinase pair and the THDA pathway may be potential therapeutic targets for PD

In contrast, Ruminococcaceae UCG-009 was present in all experimental groups, and exhibited significantly greater relative abundance in both the LD control group and the 5A-1MQ-treated group switched from WD to LD compared to the WD control group (both significant before FDR correction

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However, while senescence occurs throughout the lifespan, aging is a progressive decline in time (Zhang et al