Nutrient interactions Together with several B-vitamins (i.e., folate, vitamin B 12 , vitamin B 6 , and riboflavin), choline is required for the metabolism of nucleic acids and amino acids, and for the generation of the universal methyl group donor, S-adenosylmethionine (SAM) ( Figure 4 )
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While in vitro and animal studies indicated a potential regression of endometriotic implants and a reduction in invasion and proliferation following vitamin D supplementation, these outcomes were not mirrored in the findings of the meta-analysis
