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Depending on the cell type and physiological conditions, Arg serves multiple purposes: it supports protein synthesis, facilitates the clearance of excess ammonium (NH4+) through urea production, acts as a precursor for creatine (an energy-buffering phosphagen), contributes to the synthesis of agmatine and polyamines, or functions as a signaling molecule to regulate lysosomal AA release into the cytosol (Fung et al
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Price et al., Cell Metabolism )
*J Orthop Res.* 28(9):1155-1161
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