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ACC1 is located in the cytosol, where it plays a primary role in malonyl-CoA production and the subsequent elongation of FAs to form long-chain polyunsaturated fatty acids (PUFAs)

doi: 10.1038/193602a0 103 OrzalesiNSorcinelliRBinaghiB

Carp H, Miller F, Hoidal JR, Janoff A

The analysis of randomized trials, including 59,995 subjects without a history of CVD, revealed that the difference in homocysteine concentrations between T/T and C/C genotypes was greater in low-folate regions compared to regions with food fortification policy (3.12 vs

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