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The compound was designed to provide both high IRAP inhibitory capacity and an improved metabolic stability attributed to the introduction of an -amino acid residue adjacent to the predicted scissile peptide bond

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882 Furthermore, the AT-OPC1 probe is designed to label PKM2 at the Lys305 site and uses electrophilic reactivity for precise protein detection through gel-based proteome imaging and real-time cell imaging, offering significant potential in cancer diagnostics