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Adverse effects are primarily gastrointestinal: Nausea, vomiting, and diarrhea occur in about 59 percent of patients

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Tranexamic acid (TXA), a lysine analogue and antifibrinolytic agent, inhibits the binding of plasminogen originating from endothelial cells to keratinocytes resulting in the diminution of melanocyte activators production (e.g., arachidonic acid, prostaglandins, leukotrienes, -MSH) [6, 27, 90]

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It's also important to note that women planning pregnancy should discontinue Ozempic at least 2 months before a planned conception due to its long half-life

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