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Fasting metformin concentrations were measured after the washout period at baseline (day 1, visit 2) and after the 3 month study (day 1, visit 5) ~12 h after the last study dose (ESM Table 1)

While standard carnitine is a well-known amino acid derivative responsible for transporting fats into our cellular powerhouses, the acetylated formALCARpossesses unique biochemical properties that allow it to cross the blood-brain barrier

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We completed a gender disaggregate analysis of participants sociodemographic and cycle-wise gait speed differences, and their effects on gait speed trajectory using Pearsons chi-square, mixed-design ANOVA, and growth curve analysis (GCA)