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When the pulmonary arterial hypertension indication was pursued and approved (as Revatio), it generated additional exclusivity, though the commercial significance was modest relative to the primary erectile dysfunction market

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Unfamiliarity with withdrawing medication from a vial into a syringe and coupled with confusion between different units of measurement may have contributed to dosing errors. The adverse effects seen so far include nausea, severe vomiting and severe hypoglycemia

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